Dissemination of Clonally RelatedEscherichia coliStrains Expressing Extended-Spectrum β-Lactamase CTX-M-15
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چکیده
منابع مشابه
Dissemination of Clonally Related Escherichia coli Strains Expressing Extended-Spectrum β-Lactamase CTX-M-15
We analyzed 43 CTX-M-15-producing Escherichia coli isolates and 6 plasmids encoding the blaCTX-M-15 gene from Canada, India, Kuwait, France, Switzerland, Portugal, and Spain. Most isolates belonged to phylogroups B2 (50%) and D (25%). An EC-B2 strain of clonal complex sequence type (ST) 131 was detected in all countries; other B2 isolates corresponded to ST28, ST405, ST354, and ST695 from speci...
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We characterized extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance (PMQR) in 32 Escherichia coli extended spectrum cephalosporin (ESC)-resistant clinical isolates from UK companion animals from several clinics. In addition, to investigate the possible dissemination of ESBL clinical isolates within a veterinary hospital, two ESBL-producing E. coli isolates from ...
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We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led to sustained resolution of fever. Resource-limited hospitals can incur prohibitive costs from ESB...
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(20 min) with the inactivator, using the same reporter substrate. Inactivation by clavulanic acid was observed only after preincubation competitive assays (indirect IC501⁄456 mM). On the other hand, 3-phenyl boronic acid showed enzymatic inactivation in both competitive and pre-incubation assays at high concentrations (direct IC501⁄4390 mM and indirect IC501⁄4151 mM). INQ-1 seems to be a cephal...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2008
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1402.070350